Micro-Dosing Mescaline: Comparing San Pedro to LSD and Psilocybin

Jerry Toth
10 min readMar 15, 2020
Exactly 0.5 grams of San Pedro powder before breakfast

Whereas a high dose can fundamentally reframe your relationship with Life, a microdose of San Pedro is like Adderall infused with a subtle sense of gratitude for being alive.

I’ve written numerous other articles about the life-altering power of consuming full doses of San Pedro, and I even made a film about it — which you can watch below. This article, however, is about consuming small amounts of San Pedro during an otherwise normal day of life.

My career in harvesting, preparing, and consuming San Pedro goes back by almost two decades. But it wasn’t until this past year that I started experimenting with micro-dosing San Pedro.

Previously I had experimented with micro-dosing psilocybin mushrooms and LSD. The former was aimed at treating post-traumatic stress disorder, the latter was aimed at stimulating creativity. In both cases, the results were generally positive, although mixed.

Despite my abiding faith in and respect for San Pedro, I went into this new phase of experimentation with an open mind. And the results surprised me. I’m happy to share my findings here.

First, a disclaimer. Everyone reacts to psychedelics differently — some people favorably and other people unfavorably. Even people who tend to react favorably should…



Jerry Toth

Professional rainforest conservationist, cacao farmer, chocolate entrepreneur, and metaphysical explorer based in Ecuador.